Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | ATG7 | O95352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445372 | 1.00 | ALOX5 (0.41) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL6454601 | 1.00 | ALOX5 (0.41) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL7608078 | 1.00 | ALOX5 (0.41) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL1445371 | 1.00 | ALOX5 (0.41) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL2109207 | 0.92 | ALOX5 (0.49) | ALOX5TRIM24 | |
| SCHEMBL8554998 | 0.87 | ALOX5 (0.36) | ALOX5 | |
| SCHEMBL2108067 | 0.87 | CREBBP (0.36) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL8556070 | 0.85 | ALOX5 (0.38) | ALOX5 | |
| SCHEMBL9160052 | 0.83 | ALOX5 (0.35) | ALOX5TRIM24ALDH1A1GAACREBBP | |
| SCHEMBL2108607 | 0.80 | ALOX5 (0.44) | ALOX5TRIM24ALDH1A1GAACREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020040047-A1 | Novel Use | ASTRAZENECA AB (SE) | 2002-04-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040047-A1 | Novel Use | FPR3, NOX4, LTC4S | ALOX5 198/4885TRIM24 1644/4885ALDH1A1 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.