SCHEMBL9160147

SCHEMBL9160147

C=Cc1nccc(C)c1C

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 4/20 0.48
NOS3 P29474 3/20 0.48
CCR1 P32246 3/20 0.39
CCR5 P51681 3/20 0.39
CCR8 P51685 3/20 0.39
PDXK O00764 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
BTK Q06187 1/20 0.32
PSMD14 O00487 1/20 0.31
COPS5 Q92905 1/20 0.31
UHRF1 Q96T88 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27819567 0.84 NOS3 (0.36) NOS2NOS3PDXKBTK
SCHEMBL10426329 0.82 CCR1 (0.37) NOS2NOS3CCR1CCR5CCR8
SCHEMBL21649995 0.81 NOS3 (0.41) NOS2NOS3CCR1CCR5CCR8
SCHEMBL660758 0.81 NOS2 (0.48) NOS2NOS3CCR1CCR5CCR8
SCHEMBL4624037 0.80 CCR1 (0.35) NOS2NOS3CCR1CCR5CCR8
SCHEMBL27223150 0.80 BTK (0.37) NOS2NOS3CCR1CCR5CCR8
SCHEMBL31703268 0.80 CCR1 (0.35) NOS2NOS3CCR1CCR5CCR8
SCHEMBL21899450 0.80 NOS2 (0.54) NOS2NOS3CCR1CCR5CCR8
SCHEMBL30296511 0.80 CCR1 (0.35) NOS2NOS3CCR1CCR5CCR8
SCHEMBL27975053 0.80 CCR1 (0.35) NOS2NOS3CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100374488-C Method for preparing two-dimensional regular polymer nano-micron pore array template UNIV TSINGHUA (CN) 2008-03-12 CN claimed
CN-100335531-C Method for preparing nano micron pore array template of two-dimensional regular polymer UNIV TSINGHUA (CN) 2007-09-05 CN claimed
CN-1850890-A Method for preparing two-dimensional regular polymer nano-micron pore array template UNIV TSINGHUA (CN) 2006-10-25 CN claimed
CN-1803894-A Method for preparing nano micron pore array template of two-dimensional regular polymer UNIV TSINGHUA (CN) 2006-07-19 CN claimed
WO-2024092115-A2 MK2 INHIBITORS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2024-05-02 WO disclosed
CN-100374488-C Method for preparing two-dimensional regular polymer nano-micron pore array template UNIV TSINGHUA (CN) 2008-03-12 CN disclosed
CN-100335531-C Method for preparing nano micron pore array template of two-dimensional regular polymer UNIV TSINGHUA (CN) 2007-09-05 CN disclosed
CN-1850890-A Method for preparing two-dimensional regular polymer nano-micron pore array template UNIV TSINGHUA (CN) 2006-10-25 CN disclosed
CN-1803894-A Method for preparing nano micron pore array template of two-dimensional regular polymer UNIV TSINGHUA (CN) 2006-07-19 CN disclosed
US-5415795-A Methods for controlling dust in high temperature systems by contacting dust with an aqueous sodium silicate solution BETZ LABORATORIES, INC. (US) 1995-05-16 US disclosed
US-4006149-A COBALT CONTAINING STUDIENGESELLSCHAFT KOHLE M.B.H. (DT) 1977-02-01 US disclosed
US-3936429-A Reactive polymer FUJI PHOTO FILM CO., LTD. (JA) 1976-02-03 US disclosed