Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | CCR8 | P51685 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 4/20 | 0.35 |
| ▸ | NOS3 | P29474 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | PDXK | O00764 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26849033 | 0.84 | CCR1 (0.32) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL18754159 | 0.83 | NOS2 (0.34) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL15417589 | 0.82 | CCR1 (0.39) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL9160147 | 0.82 | NOS2 (0.48) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL25627501 | 0.80 | CCR1 (0.38) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL8437176 | 0.79 | GRM4 (0.45) | L3MBTL1 | |
| SCHEMBL8432596 | 0.79 | MLYCD (0.36) | — | |
| SCHEMBL2909172 | 0.77 | CCR1 (0.35) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL31703268 | 0.77 | CCR1 (0.35) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL12439413 | 0.77 | NOS2 (0.54) | CCR1CCR5CCR8NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085030-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED DIVINYL PYRIDINES, AND SUBSTITUTED DIVINYL PYRIDINES | CIBA-GEIGY AG (CH) | 1985-05-22 | — | — | EP | claimed |
| US-4943482-A | ADDITION COPOLYMER WITH SILVER OR PALLADIUM COATING | RHONE-POULENC CHIMIE (FR) | 1990-07-24 | — | — | US | disclosed |
| EP-0311476-A1 | Metallized particles of crosslinked functional polymers, their preparation and their use in producing electroconductive materials | RHONE-POULENC CHIMIE (FR) | 1989-04-12 | — | — | EP | disclosed |