Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167080 | 0.89 | FAAH (0.54) | FAAHNPC1MITFRAB9APAX8 | |
| SCHEMBL9432756 | 0.87 | FAAH (0.52) | FAAHNPC1MITFRAB9APAX8 | |
| SCHEMBL9165641 | 0.87 | NR1H4 (0.73) | RAB9ASMN1; SMN2NR1H4 | |
| SCHEMBL9163700 | 0.86 | NLRP3 (0.58) | NPC1RAB9ASMN1; SMN2NR1H4 | |
| SCHEMBL10597666 | 0.85 | FAAH (0.73) | FAAHPPARACA12CA1CA2 | |
| SCHEMBL9432752 | 0.83 | FAAH (0.52) | FAAHNPC1MITFRAB9APAX8 | |
| SCHEMBL4123129 | 0.83 | KDR (0.59) | NPC1MITFRAB9APAX8SMN1; SMN2 | |
| SCHEMBL9161132 | 0.81 | PLA2G4B (0.55) | SMN1; SMN2NR1H4 | |
| Bromide SCHEMBL9162043 | 0.81 | NR1H4 (0.45) | FAAHNR1H4 | |
| SCHEMBL9484705 | 0.81 | CACNA1B (0.49) | NR1H4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432189-A | Bis-aryl amide and urea antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1995-07-11 | — | — | US | disclosed |
| US-5350759-A | Bis-aryl urea compounds | WISSNER ALLAN (US) | 1994-09-27 | — | — | US | disclosed |
| US-5231182-A | Platelet activating factor inhibitor | AMERICAN CYANAMID COMPANY (US) | 1993-07-27 | — | — | US | disclosed |
| US-5225425-A | Respiratory system disorders | AMERICAN CYANAMID COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5128351-A | BIS-ARYL AMIDE AND UREA ANTAGONISTS OF PLATELET ACTIVATING FACTOR | AMERICAN CYANAMID COMPANY (US) | 1992-07-07 | — | — | US | disclosed |
| US-5077409-A | Reducing hydroxy bis-aryl amide, acylating, hydrolyzing, sulfonating, halogenating, alkylating with nitrogen heterocycle | AMERICAN CYANAMID COMPANY (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0458037-A1 | Bis-aryl amide and urea antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |