Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.94 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.94 |
| ▸ | TSHR | P16473 | 1/20 | 0.94 |
| ▸ | GAA | P10253 | 3/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 4/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736600 | 0.97 | HTT (1.00) | NPSR1HTTKMT2ACHEK1TSHR | |
| SCHEMBL914710 | 0.95 | GAA (1.00) | NPSR1HTTKMT2ACHEK1TSHR | |
| SCHEMBL2951788 | 0.81 | NPSR1 (0.68) | NPSR1HTTKMT2ACHEK1TSHR | |
| SCHEMBL914395 | 0.81 | NPSR1 (0.68) | NPSR1HTTKMT2ACHEK1TSHR | |
| SCHEMBL3637702 | 0.80 | HTT (0.67) | NPSR1HTTKMT2ACHEK1TSHR | |
| SCHEMBL4694133 | 0.80 | HTT (0.67) | NPSR1HTTKMT2ACHEK1TSHR | |
| SCHEMBL4691404 | 0.79 | HTT (0.65) | NPSR1HTTKMT2ACHEK1TSHR | |
| SCHEMBL14459794 | 0.78 | HTT (0.63) | NPSR1HTTKMT2ACHEK1TSHR | |
| SCHEMBL939440 | 0.78 | KDM4E (0.64) | NPSR1HTTKMT2ACHEK1TSHR | |
| SCHEMBL938939 | 0.78 | KDM4E (0.63) | NPSR1HTTKMT2ACHEK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340495-B | O-nitrobenzene compound and preparation method and application thereof | 华东理工大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-107629022-B | Antibacterial synergist and preparation method and application thereof | 上海医药工业研究院 | 2024-11-12 | — | — | CN | disclosed |
| CN-111087345-B | Azobenzene heterocyclic amide derivative, and preparation method and application thereof | 华东理工大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-113150053-B | Azobenzene avermectin derivative and preparation method and application thereof | 华东理工大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-114105986-B | Aromatic condensed ring diketone compound and preparation method and application thereof | 华东理工大学 | 2024-09-27 | — | — | CN | disclosed |
| WO-2024179532-A1 | ANTIBACTERIAL AND SYNERGISTIC ACTIVE COMPOUND AND USE THEREOF | 华东理工大学 | 2024-09-06 | — | — | WO | disclosed |
| CN-118557575-A | Antibacterial synergistic active compound and application thereof | 华东理工大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-116102553-A | Aromatic condensed ring imine compound, and preparation method and application thereof | 华东理工大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-115991693-A | Coumarin-containing compound and preparation method and application thereof | 华东理工大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-115124487-A | Preparation method and application of arylimino thiazole compounds | 华东理工大学 | 2022-09-30 | — | — | CN | disclosed |
| US-7872052-B2 | Use of heterocyclic compounds as SCCE inhibitors | AREXIS AB (SE) | 2011-01-18 | — | — | US | disclosed |
| EP-2257555-A1 | THIENO[2,3-D]-PYRIMIDINE-4(3H)-ONE COMPOUNDS WITH ANTIFUNGAL PROPERTIES AND PROCESS THEREOF | National Chemical Laboratory (IN) | 2010-12-08 | — | — | EP | disclosed |
| US-20100273815-A1 | THIENO[2,3-D]-PYRIMIDIN-4(3H)-ONE COMPOUNDS WITH ANTIFUNGAL PROPERTIES AND PROCESS THEREOF | FDC LIMITED | 2010-10-28 | — | — | US | disclosed |
| WO-2010075561-A1 | SMALL MOLECULE INHIBITORS OF NECROPTOSIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2009109983-A1 | THIENO[2,3-D]-PYRIMIDINE-4(3H)-ONE COMPOUNDS WITH ANTIFUNGAL PROPERTIES AND PROCESS THEREOF | NATIONAL CHEMICAL LABORATORY (IN) | 2009-09-11 | — | — | WO | disclosed |
| US-20060258651-A1 | Use of heterocyclic compounds as scce inhibitors | QUANTUM LTO HOLDINGS, LLC | 2006-11-16 | — | — | US | disclosed |
| EP-1631295-A2 | USE OF FUSED HETEROCYCLIC COMPOUNDS AS SCCE INHIBITORS FOR THE TREATMENT OF SKIN CONDITIONS OR CANCER | Arexis AB (SE) | 2006-03-08 | — | — | EP | disclosed |
| US-6849638-B2 | 4-AMINO-5,6-SUBSTITUTED THIOPHENO [2,3-D] PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND THEIR USE IN THE TREATMENT OR PREVENTION OF PDE7B-MEDIATED DISEASES AND CONDITIONS | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-02-01 | — | — | US | disclosed |
| WO-2004108139-A2 | USE OF FUSED HETEROCYCLIC COMPOUNDS AS SCCE INHIBITORS FOR THE TREATMENT OF SKIN CONDITIONS OR CANCER | AREXIS AB (SE) | 2004-12-16 | — | — | WO | disclosed |
| US-20030119829-A1 | 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same, and their use in the treatment or prevention of PDE7B-mediated diseases and conditions | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258651-A1 | Use of heterocyclic compounds as scce inhibitors | RCE1, CTSE, SPINT2 | NPSR1 1988/4885HTT 3172/4885KMT2A 2584/4885 |
| US-20030119829-A1 | 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same, and their use in the treatment or prevention of PDE7B-mediated diseases and conditions | PDE7B, PDE4B, PDE7A | NPSR1 3564/4885HTT 4454/4885KMT2A 2143/4885 |
| US-20100273815-A1 | THIENO[2,3-D]-PYRIMIDIN-4(3H)-ONE COMPOUNDS WITH ANTIFUNGAL PROPERTIES AND PROCESS THEREOF | ERG28, DPM1, CYP51A1 | NPSR1 2860/4885HTT 4006/4885KMT2A 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.