Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | CCR5 | P51681 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9161998 | 1.00 | ALOX5 (0.47) | ALOX5CCR5HTTMAOBMAOA | |
| SCHEMBL8543983 | 0.89 | ALOX5 (0.41) | ALOX5CCR5HTTMAOBALDH1A1 | |
| SCHEMBL8544488 | 0.85 | ALOX5 (0.50) | ALOX5CCR5HTTMAOBMAOA | |
| SCHEMBL8544483 | 0.85 | ALOX5 (0.50) | ALOX5CCR5HTTMAOBMAOA | |
| SCHEMBL13316590 | 0.82 | MAOB (0.44) | ALOX5MAOBALDH1A1KDM4ECASP3 | |
| SCHEMBL8543191 | 0.79 | ALOX5 (0.55) | ALOX5CCR5HTTMAOBMAOA | |
| SCHEMBL8544470 | 0.78 | ALOX5 (0.47) | ALOX5CCR5HTTMAOBMAOA | |
| SCHEMBL8544473 | 0.78 | ALOX5 (0.47) | ALOX5CCR5HTTMAOBMAOA | |
| SCHEMBL8548854 | 0.78 | ALOX5 (0.50) | ALOX5CCR5MAOBMAOANR1H4 | |
| SCHEMBL8548850 | 0.78 | ALOX5 (0.50) | ALOX5CCR5MAOBMAOANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391569-A | Treating osteoporosis, inflammatory disorders | ADIR ET COMPAGNIE (FR) | 1995-02-21 | — | — | US | disclosed |