Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.50 |
| ▸ | CCR5 | P51681 | 6/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548850 | 1.00 | ALOX5 (0.50) | ALOX5CCR5HTR1AHTR2BTMEM97 | |
| SCHEMBL8544473 | 0.82 | ALOX5 (0.47) | ALOX5CCR5TP53MAPTMAOB | |
| SCHEMBL8544483 | 0.82 | ALOX5 (0.50) | ALOX5CCR5MAPTMAOBMAOA | |
| SCHEMBL8544488 | 0.82 | ALOX5 (0.50) | ALOX5CCR5MAPTMAOBMAOA | |
| SCHEMBL8544470 | 0.82 | ALOX5 (0.47) | ALOX5CCR5TP53MAPTMAOB | |
| SCHEMBL8543191 | 0.80 | ALOX5 (0.55) | ALOX5CCR5TP53MAPTMAOB | |
| SCHEMBL9161998 | 0.78 | ALOX5 (0.47) | ALOX5CCR5MAOBMAOANR1H4 | |
| SCHEMBL9161995 | 0.78 | ALOX5 (0.47) | ALOX5CCR5MAOBMAOANR1H4 | |
| SCHEMBL31538745 | 0.77 | ALOX5 (0.57) | ALOX5CCR5TP53MAPTMAOB | |
| SCHEMBL8550221 | 0.75 | RXRA (0.47) | ALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591046-B1 | Chromene derivatives with a triene chain for use in the treatment of osteoporosis inflammatory diseases | ADIR (FR) | 1998-12-02 | — | — | EP | disclosed |
| US-5391569-A | Treating osteoporosis, inflammatory disorders | ADIR ET COMPAGNIE (FR) | 1995-02-21 | — | — | US | disclosed |
| EP-0591046-A1 | Chromene derivatives with a triene chain for use in the treatment of osteoporosis inflammatory diseases | ADIR ET COMPAGNIE (FR) | 1994-04-06 | — | — | EP | disclosed |