Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3736508 | 0.87 | MMP1 (0.44) | SMN1; SMN2MMP1MMP3MMP8PKM | |
| SCHEMBL14602765 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2MMP1MMP3MMP8PKM | |
| SCHEMBL6019241 | 0.79 | DPP7 (0.42) | MMP1MMP3MMP8ALDH1A1L3MBTL1 | |
| SCHEMBL15405711 | 0.78 | DPP7 (0.41) | MMP1MMP3MMP8ALDH1A1L3MBTL1 | |
| SCHEMBL3068967 | 0.77 | MMP1 (0.45) | SMN1; SMN2MMP1MMP3MMP8PKM | |
| SCHEMBL3062998 | 0.77 | MMP1 (0.45) | SMN1; SMN2MMP1MMP3MMP8PKM | |
| SCHEMBL3065969 | 0.77 | MMP1 (0.45) | SMN1; SMN2MMP1MMP3MMP8PKM | |
| SCHEMBL17859607 | 0.74 | PDE4A (0.46) | SMN1; SMN2MMP1MMP3MMP8GAA | |
| SCHEMBL5486914 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2MMP1MMP3MMP8PKM | |
| SCHEMBL824919 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2MMP1MMP3MMP8PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526502-B1 | PHENOLIC AMINE DEPIGMENTING AND ANTIMELANOMA AGENTS | UNIV ALBERTA (CA) | 1995-02-22 | — | — | EP | claimed |
| US-5434233-A | Polyaldaramide polymers useful for films and adhesives | KIELY DONALD E (US) | 1995-07-18 | — | — | US | disclosed |