Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602765 | 0.89 | SMN1; SMN2 (0.50) | MMP1MMP3MMP8SMN1; SMN2CA12 | |
| SCHEMBL9162803 | 0.87 | SMN1; SMN2 (0.42) | MMP1MMP3MMP8SMN1; SMN2CA12 | |
| SCHEMBL3062998 | 0.82 | MMP1 (0.45) | MMP1MMP3MMP8SMN1; SMN2CA12 | |
| SCHEMBL3068967 | 0.82 | MMP1 (0.45) | MMP1MMP3MMP8SMN1; SMN2CA12 | |
| SCHEMBL3065969 | 0.82 | MMP1 (0.45) | MMP1MMP3MMP8SMN1; SMN2CA12 | |
| SCHEMBL8241784 | 0.81 | DPP7 (0.42) | MMP1MMP3MMP8KDM4EALDH1A1 | |
| SCHEMBL3733207 | 0.79 | DPP7 (0.44) | MMP1MMP3MMP8ALDH1A1L3MBTL1 | |
| SCHEMBL5486914 | 0.78 | SMN1; SMN2 (0.48) | MMP1MMP3MMP8SMN1; SMN2CA12 | |
| SCHEMBL828715 | 0.78 | SMN1; SMN2 (0.48) | MMP1MMP3MMP8SMN1; SMN2CA12 | |
| SCHEMBL824919 | 0.78 | SMN1; SMN2 (0.48) | MMP1MMP3MMP8SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280018-A1 | Derivatives Of Hydroxamic Acid As Metalloproteinase Inhibitors | LABORATOIRES SERONO S.A. (CH) | 2010-11-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280018-A1 | Derivatives Of Hydroxamic Acid As Metalloproteinase Inhibitors | MMP3, MMP1, MMP13 | MMP1 2/4885MMP3 1/4885MMP8 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.