SCHEMBL6019241

SCHEMBL6019241

NC(=O)[C@@H](O)[C@H](O)[C@@H](O)C(=O)N1CCCCCC1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 5/20 0.42
MMP1 P03956 2/20 0.38
MMP2 P08253 2/20 0.38
MMP8 P22894 1/20 0.38
ALDH1A1 P00352 4/20 0.38
MMP3 P08254 1/20 0.38
MMP9 P14780 1/20 0.38
F2 P00734 1/20 0.37
DPP4 P27487 4/20 0.35
HPGD P15428 2/20 0.33
HTT P42858 1/20 0.33
CA2 P00918 1/20 0.32
CHKA P35790 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15405711 0.98 DPP7 (0.41) DPP7MMP1MMP2MMP8ALDH1A1
SCHEMBL3733207 0.88 DPP7 (0.44) DPP7MMP1MMP2MMP8ALDH1A1
SCHEMBL8241784 0.85 DPP7 (0.42) DPP7MMP1MMP2MMP8ALDH1A1
SCHEMBL14602772 0.80 ALDH1A1 (0.50) DPP7MMP1MMP2MMP8ALDH1A1
SCHEMBL9162803 0.79 SMN1; SMN2 (0.42) MMP1MMP8ALDH1A1MMP3L3MBTL1
SCHEMBL1539202 0.78 ALDH1A1 (0.46) DPP7MMP1MMP2MMP8ALDH1A1
SCHEMBL3404386 0.72 DPP7 (0.46) DPP7MMP1MMP2ALDH1A1MMP3
SCHEMBL8487739 0.72 MMP1 (0.49) DPP7MMP1MMP2MMP8ALDH1A1
SCHEMBL1000048 0.72 PGD (0.37) ALDH1A1
SCHEMBL28197935 0.72 DPP7 (0.48) DPP7MMP1MMP2MMP8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1569982-B1 METHOD OF PREPARING HIGH MOLECULAR WEIGHT RANDOM POLYHYDROXYPOLYAMIDES UNIV MONTANA (US) 2006-09-13 EP disclosed
EP-1569982-A1 METHOD OF PREPARING HIGH MOLECULAR WEIGHT RANDOM POLYHYDROXYPOLYAMIDES THE UNIVERSITY OF MONTANA (US) 2005-09-07 EP disclosed
US-6894135-B2 Method for preparing high molecular weight random polyhydroxypolyamides THE UNIVERSITY OF MONTANA (US) 2005-05-17 US disclosed
US-20040158029-A1 Method for preparing high molecular weight random polyhydroxypolyamides SILICON VALLEY BANK 2004-08-12 US disclosed
WO-2004052959-A1 METHOD OF PREPARING HIGH MOLECULAR WEIGHT RANDOM POLYHYDROXYPOLYAMIDES THE UNIVERSITY OF MONTANA (US) 2004-06-24 WO disclosed