Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983140 | 0.87 | HSD17B10 (0.46) | NPC1ALDH1A1RAB9AHSD17B10HPGD | |
| SCHEMBL9169894 | 0.83 | NR5A1 (0.44) | MAPTTSHRTP53KMT2AKDM4E | |
| SCHEMBL1917623 | 0.81 | MMP12 (0.51) | NPC1ALDH1A1RAB9AHSD17B10HPGD | |
| SCHEMBL6271914 | 0.76 | LMNA (0.37) | ALDH1A1HSD17B10HPGDMAPTTSHR | |
| SCHEMBL27841537 | 0.74 | FGFR1 (0.42) | NPC1ALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL3162546 | 0.72 | MMP12 (0.69) | NPC1ALDH1A1RAB9AHSD17B10HPGD | |
| SCHEMBL9172525 | 0.72 | HTR1B (0.44) | MAPTTSHRTP53KMT2AKDM4E | |
| SCHEMBL17084655 | 0.71 | ALDH1A1 (0.49) | NPC1ALDH1A1RAB9AHSD17B10HPGD | |
| SCHEMBL1967417 | 0.71 | KMT2A (0.42) | NPC1ALDH1A1RAB9AHSD17B10HPGD | |
| SCHEMBL12909170 | 0.70 | ALDH1A1 (0.62) | NPC1ALDH1A1RAB9AHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434164-A | Carbostyril derivatives and salts thereof and pharmaceutical compositions for inhibiting adhesion of thrombocytes | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0240015-B1 | Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use | OTSUKA PHARMA CO LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5008274-A | Carbostyril derivatives and salts thereof and pharmaceutical composition for inhibiting adhesion of thrombocytes | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0240015-A2 | Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-3979369-A | DIENE POLYMER | MONSANTO COMPANY (US) | 1976-09-07 | — | — | US | disclosed |