Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916153 | 0.90 | POLB (0.43) | P2RX3MAPK1GAAALDH1A1POLB | |
| SCHEMBL710383 | 0.88 | CNR1 (0.45) | ALDH1A1POLBP2RX7TP53 | |
| SCHEMBL916309 | 0.85 | P2RX3 (0.34) | P2RX3MAPK1GAAALDH1A1POLB | |
| SCHEMBL916395 | 0.82 | MAPK1 (0.38) | MAPK1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL708249 | 0.80 | HDAC1 (0.46) | GAAALDH1A1 | |
| SCHEMBL916311 | 0.80 | BRD4 (0.35) | MAPK1GAAALDH1A1POLBKMT2A | |
| SCHEMBL916625 | 0.80 | SLC6A2 (0.39) | MAPK1GAAALDH1A1POLBKMT2A | |
| SCHEMBL915366 | 0.80 | ALDH1A1 (0.36) | MAPK1ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL709821 | 0.79 | CHRM1 (0.46) | ALDH1A1HSD17B10NPC1RAB9ATP53 | |
| SCHEMBL711445 | 0.78 | PLA2G2A (0.44) | GAAALDH1A1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009428-A1 | NOVEL ANDROGENS | N.V. ORGANON (NL) | 2011-01-13 | — | — | US | disclosed |
| EP-1742912-B1 | NOVEL ANDROGENS | ORGANON NV (NL) | 2010-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009428-A1 | NOVEL ANDROGENS | NR5A1, AR, NR3C2 | P2RX3 1661/4885MAPK1 3221/4885GAA 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.