Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 14/20 | 0.47 |
| ▸ | PPARD | Q03181 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163571 | 0.92 | HTT (0.57) | LMNAALDH1A1TSHRMAPK1HTT | |
| SCHEMBL9163297 | 0.88 | NPC1 (0.50) | LMNAALDH1A1HTTPPARAPPARD | |
| SCHEMBL9281638 | 0.88 | PPARA (0.48) | LMNAALDH1A1TSHRMAPK1HTT | |
| SCHEMBL9158377 | 0.87 | SMN1; SMN2 (0.50) | LMNATSHRMAPK1HTTPPARA | |
| SCHEMBL9163269 | 0.87 | PPARA (0.46) | PPARAPPARDPPARGMEN1PKM | |
| SCHEMBL9158327 | 0.87 | PPARA (0.49) | LMNAALDH1A1PPARAPPARDPPARG | |
| SCHEMBL9161851 | 0.86 | CYP1A2 (0.50) | ALDH1A1TSHRPPARAPPARDPPARG | |
| SCHEMBL9163536 | 0.84 | HRH4 (0.48) | LMNAALDH1A1PPARAPPARDPPARG | |
| SCHEMBL9302568 | 0.83 | ALDH1A1 (0.49) | LMNAALDH1A1TSHRMAPK1HTT | |
| SCHEMBL9163588 | 0.83 | LMNA (0.47) | LMNAHTTPPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460472-B1 | Carbamic acid derivatives, their production and use | SUMITOMO CHEMICAL CO (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5346920-A | Insecticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0460472-A1 | Carbamic acid derivatives, their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-12-11 | — | — | EP | disclosed |