SCHEMBL9163536

SCHEMBL9163536

CCCCCOC(=O)NCCOc1ccc(Oc2ccccc2)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.48
HRH3 Q9Y5N1 1/20 0.48
PPARA Q07869 11/20 0.47
PPARG P37231 7/20 0.47
PPARD Q03181 6/20 0.47
LTA4H P09960 1/20 0.46
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
EPHX2 P34913 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9163269 0.93 PPARA (0.46) HRH4HRH3PPARAPPARGPPARD
SCHEMBL9163297 0.89 NPC1 (0.50) PPARAPPARGPPARDNPC1LMNA
SCHEMBL9161851 0.87 CYP1A2 (0.50) HRH4HRH3PPARAPPARGPPARD
SCHEMBL9158327 0.86 PPARA (0.49) PPARAPPARGPPARDLTA4HLMNA
SCHEMBL9163328 0.84 LMNA (0.49) PPARAPPARGPPARDLMNAALDH1A1
SCHEMBL8651906 0.84 PPARA (0.49) PPARAPPARGPPARDLMNASMN1; SMN2
SCHEMBL9163588 0.82 LMNA (0.47) HRH4HRH3PPARAPPARGPPARD
SCHEMBL9159900 0.82 HRH4 (0.46) HRH4HRH3PPARAPPARGPPARD
SCHEMBL9165238 0.82 MEN1 (0.52) PPARAPPARGPPARDNPC1LMNA
SCHEMBL9158377 0.82 SMN1; SMN2 (0.50) PPARAPPARGPPARDLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460472-B1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL CO (JP) 1995-03-08 EP disclosed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US disclosed
EP-0460472-A1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-11 EP disclosed