Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11937039 | 0.77 | TTR (0.52) | CA1CA2CA9L3MBTL1TTR | |
| SCHEMBL28833405 | 0.75 | CA12 (0.45) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL8771792 | 0.75 | CA12 (0.40) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL2229729 | 0.73 | ACHE (0.44) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL31199227 | 0.73 | S100A4 (0.47) | KMT2AMAPTALDH1A1 | |
| SCHEMBL31199233 | 0.73 | ACHE (0.44) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL9164065 | 0.73 | S100A4 (0.47) | KMT2AMAPTALDH1A1 | |
| SCHEMBL68062 | 0.70 | PTPRC (0.72) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL69805 | 0.70 | PTPRC (0.72) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL598301 | 0.69 | TTR (0.88) | L3MBTL1TTRPTPRCPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430164-B1 | Process for preparation of 2-substituted-1,4-naphthoquinone | NIPPON CATALYTIC CHEM IND (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5329026-A | Oxidation of substituted naphthoquinone, adding a diene compound to reaction product, separation | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |