SCHEMBL91634

SCHEMBL91634

C=CC(=O)Oc1ccc2c(c1)c1cc3c(cc1n2CC)C(=O)CCS3

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.42
HTT P42858 2/20 0.42
PTGER4 P35408 2/20 0.39
POLB P06746 1/20 0.38
PKM P14618 1/20 0.38
ALDH1A1 P00352 6/20 0.36
HSD17B10 Q99714 3/20 0.34
MAPK1 P28482 2/20 0.34
THRB P10828 2/20 0.34
HPGD P15428 4/20 0.34
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TSHR P16473 2/20 0.33
RYR2 Q92736 1/20 0.33
RAB9A P51151 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL86366 0.78 ALDH1A1 (0.47) KDM4EHTTPOLBPKMALDH1A1
SCHEMBL13339009 0.77 VHL (0.50) KDM4EHTTPOLBALDH1A1THRB
SCHEMBL29037955 0.75 KDM4E (0.52) KDM4EHTTPOLBPKMALDH1A1
SCHEMBL18533298 0.67 MAPT (0.46) KDM4EHTTPOLBPKMALDH1A1
SCHEMBL87196 0.66 KDM4E (0.32) KDM4EALDH1A1
SCHEMBL87202 0.66 ALDH1A1 (0.49) KDM4EHTTPOLBPKMALDH1A1
SCHEMBL13909546 0.65 KDM4E (0.53) KDM4EHTTPTGER4POLBPKM
SCHEMBL31219198 0.65 LMNA (0.51) KDM4EPKMALDH1A1MAPK1THRB
SCHEMBL87106 0.65 THRB (0.38) KDM4EHTTALDH1A1THRBLMNA
SCHEMBL10050688 0.64 KDM4E (0.48) KDM4EHTTPOLBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053095-B2 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2017-02-22 EP disclosed
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 KDM4E 679/4885HTT 3488/4885PTGER4 1485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.