Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163309 | 0.95 | PPARD (0.43) | HRH4HRH3PPARDPPARAEPHX2 | |
| SCHEMBL9163409 | 0.89 | PPARA (0.43) | HRH4HRH3PPARDPPARAEPHX2 | |
| SCHEMBL9161951 | 0.89 | HRH4 (0.42) | HRH4HRH3PPARDPPARAEPHX2 | |
| SCHEMBL9157654 | 0.89 | HRH4 (0.42) | HRH4HRH3PPARDPPARAEPHX2 | |
| SCHEMBL9165279 | 0.89 | PPARA (0.44) | HRH4HRH3PPARDPPARAEPHX2 | |
| SCHEMBL9160265 | 0.88 | HRH4 (0.43) | HRH4HRH3PPARDPPARAEPHX2 | |
| SCHEMBL9163570 | 0.88 | L3MBTL1 (0.45) | PPARDPPARAEPHX2MAPK1L3MBTL1 | |
| SCHEMBL9160000 | 0.87 | MAPT (0.46) | PPARDPPARAMAPK1L3MBTL1TP53 | |
| SCHEMBL9162114 | 0.87 | HTT (0.48) | HRH4HRH3PPARDPPARAEPHX2 | |
| SCHEMBL9165467 | 0.87 | LMNA (0.43) | HRH4HRH3PPARDPPARAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460472-B1 | Carbamic acid derivatives, their production and use | SUMITOMO CHEMICAL CO (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5346920-A | Insecticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-09-13 | — | — | US | disclosed |
| EP-0460472-A1 | Carbamic acid derivatives, their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-12-11 | — | — | EP | disclosed |