Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPME1 | Q9Y570 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9163544 | 1.00 | PPME1 (0.46) | PPME1ALDH1A1POLBEGFRPKM | |
| SCHEMBL8755116 | 0.84 | PKM (0.44) | PPME1ALDH1A1POLBEGFRPKM | |
| SCHEMBL8755120 | 0.84 | PKM (0.44) | PPME1ALDH1A1POLBEGFRPKM | |
| SCHEMBL9163842 | 0.84 | PPME1 (0.58) | PPME1ALDH1A1POLBEGFRPKM | |
| SCHEMBL4144063 | 0.82 | NEK2 (0.49) | PPME1ALDH1A1POLBEGFRPKM | |
| SCHEMBL4144065 | 0.82 | NEK2 (0.49) | PPME1ALDH1A1POLBEGFRPKM | |
| SCHEMBL4179092 | 0.70 | HPGD (0.54) | ALDH1A1PKMKMT2AHPGDKDM4E | |
| SCHEMBL4179080 | 0.70 | HPGD (0.54) | ALDH1A1PKMKMT2AHPGDKDM4E | |
| SCHEMBL4179090 | 0.70 | HPGD (0.54) | ALDH1A1PKMKMT2AHPGDKDM4E | |
| SCHEMBL4071042 | 0.69 | HPGD (0.51) | ALDH1A1POLBEGFRPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410630-A | Optical article containing a polymer exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (US) | 1995-04-25 | — | — | US | disclosed |