Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK2 | P51955 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PPME1 | Q9Y570 | 5/20 | 0.43 |
| ▸ | APEH | P13798 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144063 | 1.00 | NEK2 (0.49) | NEK2EGFRPKML3MBTL1HPGD | |
| SCHEMBL11560494 | 0.82 | PPME1 (0.55) | NEK2EGFRPKML3MBTL1HPGD | |
| SCHEMBL11560496 | 0.82 | PPME1 (0.55) | NEK2EGFRPKML3MBTL1HPGD | |
| SCHEMBL9163544 | 0.82 | PPME1 (0.46) | NEK2EGFRPKML3MBTL1HPGD | |
| SCHEMBL9163553 | 0.82 | PPME1 (0.46) | NEK2EGFRPKML3MBTL1HPGD | |
| SCHEMBL9162134 | 0.80 | ALDH1A1 (0.60) | NEK2EGFRPKML3MBTL1HPGD | |
| SCHEMBL9162141 | 0.80 | ALDH1A1 (0.60) | NEK2EGFRPKML3MBTL1HPGD | |
| SCHEMBL8755120 | 0.79 | PKM (0.44) | NEK2EGFRPKML3MBTL1HPGD | |
| SCHEMBL8755116 | 0.79 | PKM (0.44) | NEK2EGFRPKML3MBTL1HPGD | |
| SCHEMBL9160732 | 0.74 | KDM4E (0.47) | NEK2PKMHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484051-B1 | Use of at least one blue-light screening agent to preserve the amount of endogenous carotenoids in the skin, new blue- light screening agents, cosmetic compositions. | OREAL (FR) | 2013-08-21 | — | — | EP | disclosed |
| US-20090074820-A1 | AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF | L'OREAL (FR) | 2009-03-19 | — | — | US | disclosed |
| US-7390916-B2 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2008-06-24 | — | — | US | disclosed |
| US-20070249853-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2007-10-25 | — | — | US | disclosed |
| US-7255853-B2 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2007-08-14 | — | — | US | disclosed |
| EP-1269979-B1 | Aromatic amide, sulfonamide or carbamate acrylonitrile derivatives and photoprotective cosmetic compositions containing them | OREAL (FR) | 2005-11-16 | — | — | EP | disclosed |
| US-20050008588-A1 | Aminoarylvinyl-s-triazine compounds and uses thereof | L'OREAL (FR) | 2005-01-13 | — | — | US | disclosed |
| EP-1484051-A2 | Use of at least one blue-light screening agent to preserve the amount of endogenous carotenoids in the skin, new blue- light screening agents, cosmetic compositions. | L'OREAL (FR) | 2004-12-08 | — | — | EP | disclosed |
| US-20040175337-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2004-09-09 | — | — | US | disclosed |
| US-6749839-B2 | TOPICAL SUNSCREENS FOR HAIR OR SKIN | L'OREAL (FR) | 2004-06-15 | — | — | US | disclosed |
| US-20030031691-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2003-02-13 | — | — | US | disclosed |
| EP-1269979-A1 | Aromatic amide, sulfonamide or carbamate acrylonitrile derivatives and photoprotective cosmetic compositions containing them | L'OREAL (FR) | 2003-01-02 | — | — | EP | disclosed |
| US-5410630-A | Optical article containing a polymer exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040175337-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | CBR3, CBR1, H1-10 | NEK2 4642/4885EGFR 934/4885PKM 3452/4885 |
| US-20030031691-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | CBR3, CBR1, NAA50 | NEK2 4638/4885EGFR 954/4885PKM 3456/4885 |
| US-20070249853-A1 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | CBR3, C1R, H1-3 | NEK2 3737/4885EGFR 677/4885PKM 3074/4885 |
| US-20050008588-A1 | Aminoarylvinyl-s-triazine compounds and uses thereof | TYR, AAAS, ALAD | NEK2 1123/4885EGFR 1706/4885PKM 4531/4885 |
| US-20090074820-A1 | AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF | TYR, AAAS, ALAD | NEK2 1292/4885EGFR 1614/4885PKM 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.