Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | UCHL3 | P15374 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848958 | 0.76 | MAOB (0.46) | L3MBTL1TAAR1LMNAMAOB | |
| SCHEMBL139408 | 0.71 | L3MBTL1 (0.56) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL3205913 | 0.71 | TYR (0.44) | S1PR1S1PR3UCHL3L3MBTL1HTR2A | |
| SCHEMBL1611282 | 0.71 | IDO1 (0.40) | S1PR1S1PR3UCHL3L3MBTL1HTR2A | |
| SCHEMBL9214298 | 0.71 | SLC6A2 (0.44) | L3MBTL1TAAR1LMNAMAOB | |
| SCHEMBL9212318 | 0.70 | HTR2A (0.50) | UCHL3HTR2ALMNA | |
| SCHEMBL8091009 | 0.69 | HTR2A (0.56) | UCHL3HTR2ALMNA | |
| SCHEMBL1610696 | 0.69 | IDO1 (0.39) | S1PR1S1PR3UCHL3L3MBTL1HTR2A | |
| SCHEMBL1611347 | 0.69 | IDO1 (0.39) | S1PR1S1PR3UCHL3L3MBTL1HTR2A | |
| SCHEMBL5413888 | 0.69 | TYR (0.45) | TSHRMAPK1ATML3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459142-A | Autoimmune disease, atherosclerosis, antiischemic agents and nephritis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |