Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | UCHL3 | P15374 | 2/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249124 | 0.94 | TYR (0.45) | TYRRAB9ANPC1SMN1; SMN2S1PR1 | |
| SCHEMBL933030 | 0.86 | TYR (0.48) | TYRRAB9ANPC1SMN1; SMN2IDO1 | |
| SCHEMBL869709 | 0.86 | TYR (0.48) | TYRRAB9ANPC1SMN1; SMN2IDO1 | |
| Propionaldehyde SCHEMBL4619414 | 0.81 | TYR (0.44) | TYRRAB9ANPC1SMN1; SMN2IDO1 | |
| SCHEMBL6567210 | 0.81 | GPR84 (0.42) | LMNAALDH1A1HTR2AEPHX1 | |
| SCHEMBL1611282 | 0.81 | IDO1 (0.40) | TYRRAB9ANPC1SMN1; SMN2S1PR1 | |
| SCHEMBL19043222 | 0.80 | LMNA (0.37) | RAB9ANPC1SMN1; SMN2LMNAPKM | |
| SCHEMBL1610696 | 0.80 | IDO1 (0.39) | TYRRAB9ANPC1SMN1; SMN2S1PR1 | |
| SCHEMBL1611347 | 0.80 | IDO1 (0.39) | TYRRAB9ANPC1SMN1; SMN2S1PR1 | |
| SCHEMBL5543511 | 0.79 | HDAC3 (0.49) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030835-B2 | Substituted amide compounds useful as farnesoid X receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-09 | — | — | US | disclosed |
| US-20220213026-A1 | SUBSTITUTED AMIDE COMPOUNDS USEFUL AS FARNESOID X RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2022-07-07 | — | — | US | disclosed |
| US-7678752-B2 | Fabric care composition comprising organosilicone microemulsion and anionic/nitrogen-containing surfactant system | THE PROCTER & GAMBLE COMPANY (US) | 2010-03-16 | — | — | US | disclosed |
| EP-1313828-B2 | FABRIC CARE COMPOSITIONS COMPRISING CATIONIC SILICONES AND METHODS EMPLOYING SAME | PROCTER & GAMBLE (US) | 2009-10-14 | — | — | EP | disclosed |
| US-7384903-B2 | Fabric care and perfume compositions and systems comprising cationic silicones and methods employing same | THE PROCTER & GAMBLE COMPANY (US) | 2008-06-10 | — | — | US | disclosed |
| US-20070225198-A1 | Fabric care compositions and systems comprising organosilicone microemulsions and methods employing same | PROCTER & GAMBLE COMPANY, THE | 2007-09-27 | — | — | US | disclosed |
| EP-1221440-B1 | Benzoheterocyclic derivatives useful as vasopressin or oxytocin modulators | OTSUKA PHARMA CO LTD (JP) | 2007-04-25 | — | — | EP | disclosed |
| EP-1313828-B1 | FABRIC CARE COMPOSITIONS COMPRISING CATIONIC SILICONES AND METHODS EMPLOYING SAME | PROCTER & GAMBLE (US) | 2006-10-11 | — | — | EP | disclosed |
| US-6903061-B2 | Fabric care and perfume compositions and systems comprising cationic silicones and methods employing same | THE PROCTER & GAMBLE COMPANY (US) | 2005-06-07 | — | — | US | disclosed |
| US-6642223-B2 | A benzoazepin or benzodiazepin derivatives, shows excellent anti-vasopressin activity, vasopressin agonistic activity and oxytocin antagonistic activity, and are useful as antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| US-20020103094-A1 | Fabric care and perfume compositions and systems comprising cationic silicones and methods employing same | THE PROCTER & GAMBLE COMPANY | 2002-08-01 | — | — | US | disclosed |
| EP-1221440-A1 | Benzoheterocyclic derivatives useful as vasopressin or oxytocin modulators | Otsuka Pharmaceutical Company, Limited (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-20020049194-A1 | Benzoheterocyclic derivatives | OGAWA HIDENORI (JP) | 2002-04-25 | — | — | US | disclosed |
| US-6335327-B1 | Benzoheterocyclic derivatives | OTSUKA PHARMACEUTICALS CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| US-6096735-A | Benzoheterocyclic derivatives | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-08-01 | — | — | US | disclosed |
| EP-0765314-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995034540-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213026-A1 | SUBSTITUTED AMIDE COMPOUNDS USEFUL AS FARNESOID X RECEPTOR MODULATORS | FXR1, NR1H4, FXR2 | TYR 3654/4885RAB9A 1240/4885NPC1 290/4885 |
| US-20020049194-A1 | Benzoheterocyclic derivatives | AVPR2, AVPR1A, AVPR1B | TYR 3647/4885RAB9A 1825/4885NPC1 2978/4885 |
| US-12030835-B2 | Substituted amide compounds useful as farnesoid X receptor modulators | FXR1, NR1H4, FXR2 | TYR 3654/4885RAB9A 1240/4885NPC1 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.