Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214298 | 0.95 | SLC6A2 (0.44) | MAOBL3MBTL1MAOASLC6A2TAAR1 | |
| Ammonia Solution, Strong SCHEMBL27427966 | 0.83 | DNM1 (0.44) | SLC6A2TAAR1SIGMAR1LMNACYP2D6 | |
| SCHEMBL7768774 | 0.80 | CHRM2 (0.43) | MAOBL3MBTL1MAOASLC6A2SIGMAR1 | |
| SCHEMBL9164089 | 0.76 | S1PR1 (0.34) | MAOBL3MBTL1TAAR1LMNA | |
| SCHEMBL28157264 | 0.75 | SLC6A2 (0.50) | MAOBSLC6A2TAAR1MMP8LMNA | |
| SCHEMBL11253562 | 0.73 | SLC6A2 (0.48) | SLC6A2TAAR1MMP8LMNACYP2D6 | |
| SCHEMBL5570918 | 0.73 | L3MBTL1 (0.40) | MAOBL3MBTL1MAOASLC6A2SIGMAR1 | |
| SCHEMBL1478014 | 0.72 | SIGMAR1 (0.52) | MAOBL3MBTL1MAOASIGMAR1 | |
| SCHEMBL7405977 | 0.72 | GPR52 (0.41) | SLC6A2TAAR1 | |
| SCHEMBL9560040 | 0.71 | SIGMAR1 (0.55) | MAOBL3MBTL1MAOASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |