Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164874 | 1.00 | MCL1 (0.43) | MCL1ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL8876470 | 0.84 | CYSLTR1 (0.44) | MCL1ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8876466 | 0.84 | CYSLTR1 (0.44) | MCL1ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9161739 | 0.81 | STING1 (0.58) | SMN1; SMN2KDM4EMEN1KMT2AGLA | |
| SCHEMBL12298542 | 0.81 | KDM4E (0.51) | ALDH1A1SMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL9567472 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL9567471 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EHPGDMAPT | |
| SCHEMBL9164443 | 0.74 | ALDH1A1 (0.68) | MCL1ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL9164440 | 0.74 | ALDH1A1 (0.68) | MCL1ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL14266190 | 0.73 | LMNA (0.52) | MCL1ALDH1A1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409952-A | Anticancer agents | ADIR ET COMPAGNIE (FR) | 1995-04-25 | — | — | US | disclosed |