Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9162488 | 0.85 | MEN1 (0.47) | KDM4EALDH1A1GAAHPGDMAOB | |
| SCHEMBL9162496 | 0.85 | MEN1 (0.47) | KDM4EALDH1A1GAAHPGDMAOB | |
| SCHEMBL9165469 | 0.78 | MAPT (0.39) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9165481 | 0.78 | MAPT (0.39) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9163981 | 0.77 | LTB4R (0.42) | LTB4RL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL9163987 | 0.77 | LTB4R (0.42) | LTB4RL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL9164164 | 0.75 | NFE2L2 (0.44) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9164174 | 0.75 | NFE2L2 (0.44) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL9166291 | 0.74 | MEN1 (0.50) | KDM4EALDH1A1HPGDMAOBMEN1 | |
| SCHEMBL9166285 | 0.74 | MEN1 (0.50) | KDM4EALDH1A1HPGDMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409952-A | Anticancer agents | ADIR ET COMPAGNIE (FR) | 1995-04-25 | — | — | US | disclosed |