Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165469 | 1.00 | MAPT (0.39) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL9165474 | 0.78 | MAPT (0.38) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL9162496 | 0.78 | MEN1 (0.47) | ALDH1A1KDM4EHPGDGAAMAOA | |
| SCHEMBL9162488 | 0.78 | MEN1 (0.47) | ALDH1A1KDM4EHPGDGAAMAOA | |
| SCHEMBL8876466 | 0.69 | CYSLTR1 (0.44) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL9163981 | 0.69 | LTB4R (0.42) | MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL9163987 | 0.69 | LTB4R (0.42) | MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL9164869 | 0.69 | MCL1 (0.43) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL9164164 | 0.68 | NFE2L2 (0.44) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL9164174 | 0.68 | NFE2L2 (0.44) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5409952-A | Anticancer agents | ADIR ET COMPAGNIE (FR) | 1995-04-25 | — | — | US | disclosed |