SCHEMBL9165686

SCHEMBL9165686

Cc1cc(CCC(=O)NN)cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 4/20 0.41
HPGD P15428 4/20 0.41
LMNA P02545 3/20 0.41
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
HIF1A Q16665 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.37
TP53 P04637 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9501982 0.88 GAA (0.41) GAANPC1RAB9AKDM4EALDH1A1
SCHEMBL9291355 0.85 GAA (0.64) GAANPC1RAB9AKDM4EALDH1A1
SCHEMBL10752939 0.85 KDM4E (0.49) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL9375817 0.81 NPC1 (0.51) GAANPC1RAB9AKDM4EALDH1A1
SCHEMBL74479 0.80 NPC1 (0.50) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL30240966 0.80 NPC1 (0.50) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL14997996 0.79 ALOX5 (0.46) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL9291461 0.78 NPC1 (0.36) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL755804 0.78 GAA (0.64) GAAKDM4EALDH1A1LMNAPOLB
SCHEMBL74902 0.78 NPC1 (0.48) NPC1RAB9AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0370501-B1 Polymer bound light stabilizer coating resins ATOCHEM NORTH AMERICA (US) 1995-04-05 EP disclosed
EP-0303988-B1 POLYMER BOUND UV STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1993-05-12 EP disclosed
US-5206378-A Ultraviolet light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-04-27 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4981914-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4975494-A USING HYDRAZIDE COMPOUND ATOCHEM OF NORTH AMERICA, INC. (US) 1990-12-04 US disclosed
EP-0370501-A2 Polymer bound light stabilizer coating resins ELF ATOCHEM NORTH AMERICA, INC. (US) 1990-05-30 EP disclosed
US-4927891-A REACTING LIGHT STABILIZER HYDRAZIDES WITH ACRYLIC RESINS PENNWALT CORPORATION (US) 1990-05-22 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0303988-A2 Polymer bound UV stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed