Chloromethane

Chloromethane

SCHEMBL9166183

C=C(CCC)C(N)=O.CCl

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
HDAC3 O15379 4/20 0.38
HDAC1 Q13547 4/20 0.38
HDAC2 Q92769 4/20 0.38
HDAC8 Q9BY41 4/20 0.38
FFAR3 O14843 3/20 0.38
CTSD P07339 1/20 0.37
ALDH1A1 P00352 4/20 0.35
TP53 P04637 2/20 0.33
HDAC6 Q9UBN7 1/20 0.33
FAAH O00519 3/20 0.31
LMNA P02545 2/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL422556 0.95
Dimethylamine SCHEMBL27527748 0.93 CTSD (0.38) TSHRCES2CES1TDP1HDAC3
Methylamine SCHEMBL4377431 0.92 CES2 (0.41) TSHRCES2CES1TDP1HDAC3
SCHEMBL28204586 0.92
Ammonia Solution, Strong SCHEMBL8445489 0.92
Water SCHEMBL28252944 0.92
Hydrochloric Acid SCHEMBL6461485 0.92
Hydrochloric Acid SCHEMBL1040510 0.90 CES2 (0.39) TSHRCES2CES1TDP1HDAC3
Hydrochloric Acid SCHEMBL28109007 0.90 CES2 (0.39) TSHRCES2CES1TDP1HDAC3
Ethylamine SCHEMBL4365157 0.90 CES2 (0.39) TSHRCES2CES1TDP1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5384196-A Polyarylene sulfide composite materials and preparation thereof TOSOH CORPORATION (JP) 1995-01-24 US disclosed