Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493979 | 0.88 | KDM4E (0.36) | CYP2C9ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL9493973 | 0.88 | KDM4E (0.36) | CYP2C9ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL9166203 | 0.88 | KDM4E (0.36) | CYP2C9ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL10532005 | 0.83 | GAA (0.35) | CYP2C9ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL9174206 | 0.83 | GAA (0.35) | CYP2C9ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL29935072 | 0.82 | KDM4E (0.39) | CYP2C9ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL9055883 | 0.82 | KDM4E (0.39) | CYP2C9ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL4650916 | 0.81 | KDM4E (0.38) | CYP2C9ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL15255890 | 0.80 | KDM4E (0.37) | CYP2C9ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL27878839 | 0.80 | KDM4E (0.37) | CYP2C9ALDH1A1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281611-B1 | LIQUID CRYSTAL PHASES FOR ELECTRO-OPTIC DISPLAY ELEMENTS BASED ON THE ECB EFFECT | MERCK PATENT GMBH (DE) | 1993-11-24 | — | — | EP | disclosed |
| EP-0281611-A1 | LIQUID CRYSTAL PHASES FOR ELECTRO-OPTIC DISPLAY ELEMENTS BASED ON THE ECB EFFECT. | MERCK PATENT GMBH (DE) | 1988-09-14 | — | — | EP | disclosed |