Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413232 | 0.98 | LDHA (0.51) | LDHAPPARAHTTMMP1MMP13 | |
| SCHEMBL28246723 | 0.98 | LDHA (0.51) | LDHAPPARAHTTMMP1MMP13 | |
| SCHEMBL20269317 | 0.85 | SMN1; SMN2 (0.49) | LDHAHTTMMP1MMP13NPC1 | |
| SCHEMBL28136422 | 0.85 | LDHA (0.53) | LDHAPPARAHTTMMP1MMP13 | |
| SCHEMBL7676911 | 0.84 | LDHA (0.51) | LDHAPPARAHTTMMP1MMP13 | |
| SCHEMBL13903099 | 0.84 | PTPRB (0.54) | LDHAHTTMMP1MMP13NPC1 | |
| SCHEMBL3739737 | 0.84 | LDHA (0.51) | LDHAPPARAHTTMMP1MMP13 | |
| SCHEMBL5208103 | 0.83 | LDHA (0.55) | LDHAHTTNPC1RAB9APOLB | |
| SCHEMBL1424653 | 0.82 | BLM (0.67) | LDHAPPARAHTTMMP1MMP13 | |
| SCHEMBL2033365 | 0.82 | BLM (0.67) | LDHAPPARAHTTMMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230046065-A1 | MERGING C(sp3)-H ACTIVATION WITH DNA-ENCODING | THE SCRIPPS RESEARCH INSTITUTE | 2023-02-16 | — | — | US | disclosed |
| CN-108586500-A | Zinc co-ordination complex and the method for preparing organic zinc reagent | 慕尼黑路德维希马克西米利安斯大学 | 2018-09-28 | — | — | CN | disclosed |
| CN-103429598-B | Organozinc complexes and methods of making and using the same | 慕尼黑路德维希马克西米利安斯大学 | 2018-03-30 | — | — | CN | disclosed |
| EP-2065360-B1 | Use of 3-methylbenzyl isobutyrate as a fragrance compound | SYMRISE AG (DE) | 2013-06-19 | — | — | EP | disclosed |
| US-7902394-B2 | Calcilytic compounds | GLAXOSMITHKLINE LLC (US) | 2011-03-08 | — | — | US | disclosed |
| US-20100029782-A1 | Calcilytic Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-04 | — | — | US | disclosed |
| EP-2120898-A1 | CALCILYTIC COMPOUNDS | SmithKline Beecham Corporation (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-2065360-A2 | 3-methylbenzyl isobutyrate | Symrise GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-1747186-B1 | Fragrant composition comprising 3-methylbenzyl-isobutyrat | SYMRISE GMBH & CO KG (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008077009-A1 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |
| CN-1221401-A | Calcilytic compounds | NPS PHARMA INC (US) | 1999-06-30 | — | — | CN | disclosed |
| EP-0901459-A1 | CALCILYTIC COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997037967-A1 | CALCILYTIC COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 1997-10-16 | — | — | WO | disclosed |
| EP-0421759-B1 | Method for producing 1-indanone derivatives | HOECHST CELANESE CORP (US) | 1995-06-07 | — | — | EP | disclosed |
| US-5179229-A | Preparation of 2,2-diorgano-3-arylpropionic acids and esters thereof | HOECHST CELANESE CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| US-5012007-A | Method for producing 1-indanone derivatives | HOECHST CELANESE CORPORATION, A CORP. OF DE | 1991-04-30 | — | — | US | disclosed |
| EP-0421759-A2 | Method for producing 1-indanone derivatives | HOECHST CELANESE CORPORATION (US) | 1991-04-10 | — | — | EP | disclosed |
| US-4898608-A | Pyridylthio-acylanilide herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-06 | — | — | US | disclosed |
| US-4797146-A | INSECTICIDES, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| US-4627871-A | Herbicidal 2-[4-substituted carboxyamino-phenoxy (or phenyl mercapto)]-substituted pyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029782-A1 | Calcilytic Compounds | CALCR, CALCA, CALCB | LDHA 3727/4885PPARA 3735/4885HTT 4483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.