Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.44 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9168342 | 0.89 | MAPT (0.50) | MAPTLMNAALDH1A1KDM4ECYP2C19 | |
| SCHEMBL9624029 | 0.88 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4ECYP2C19CYP3A4 | |
| SCHEMBL9165998 | 0.80 | ALDH1A1 (0.61) | MAPTLMNAALDH1A1KDM4ECYP2C19 | |
| SCHEMBL9161049 | 0.79 | MAPT (0.53) | MAPTLMNAALDH1A1KDM4ECYP2C19 | |
| SCHEMBL9161015 | 0.79 | TSHR (0.43) | MAPTLMNAALDH1A1KDM4ECYP2C19 | |
| SCHEMBL2213718 | 0.78 | MEN1 (0.57) | MAPTLMNAALDH1A1KDM4ECYP2C19 | |
| SCHEMBL6229506 | 0.77 | MAPT (0.56) | MAPTLMNAALDH1A1KDM4ECYP2C19 | |
| SCHEMBL8330027 | 0.77 | MAPT (0.62) | MAPTLMNAALDH1A1KDM4ECYP2C19 | |
| SCHEMBL9623907 | 0.75 | MAPT (0.51) | MAPTLMNAALDH1A1CYP2C19MEN1 | |
| SCHEMBL23407458 | 0.74 | ALOX5 (0.52) | MAPTLMNAALDH1A1KDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175340-A | Sunscreen agents, stabilizers | L'OREAL (FR) | 1992-12-29 | — | — | US | claimed |
| EP-0350386-B1 | UNSATURATED DERIVATIVES OF LIPID SOLUBLE BENZAL MALONATES, AND THEIR USE AS UV ABSORBERS IN THE COSMETIC FIELD | L'OREAL (FR) | 1992-04-08 | — | — | EP | claimed |
| US-5415854-A | Sunscreen agents | L'OREAL (FR) | 1995-05-16 | — | — | US | disclosed |
| US-5175340-A | Sunscreen agents, stabilizers | L'OREAL (FR) | 1992-12-29 | — | — | US | disclosed |
| US-5053290-A | DIORGANOPOLYSILOXANES COMPRISING BENZALMALONATE FUNCTIONAL GROUPS | RHONE-POULENC CHIMIE (FR) | 1991-10-01 | — | — | US | disclosed |