Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL9026618 | 0.84 | LDHA (0.35) | ALDH1A1 | |
| SCHEMBL9164429 | 0.75 | CTBP2 (0.49) | — | |
| Butane SCHEMBL9159515 | 0.73 | — | — | |
| Acetamide SCHEMBL27868109 | 0.73 | GAA (0.61) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL15376 | 0.73 | — | — | |
| SCHEMBL30741390 | 0.73 | GAA (0.74) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28637253 | 0.72 | APOBEC3A (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL11097044 | 0.71 | GAA (0.70) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL3201235 | 0.71 | GAA (0.70) | MGAMGAASIMGAM2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL8767262 | 0.71 | GAA (0.70) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459142-A | Autoimmune disease, atherosclerosis, antiischemic agents and nephritis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0511879-B1 | Pyrazine derivatives | OTSUKA PHARMA CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |