Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166257 | 0.84 | MGAM (0.40) | ALDH1A1 | |
| SCHEMBL8862881 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TDP1CA2 | |
| SCHEMBL8862880 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TDP1CA2 | |
| SCHEMBL14403015 | 0.73 | ALDH1A1 (0.40) | CACNA2D1CACNB3CACNA1CALDH1A1TDP1 | |
| SCHEMBL11328029 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TDP1CA2CYP2D6CYP2C19 | |
| SCHEMBL11328030 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TDP1CA2CYP2D6CYP2C19 | |
| SCHEMBL11417640 | 0.69 | ALDH1A1 (0.37) | ALDH1A1TDP1CA2 | |
| SCHEMBL11417638 | 0.69 | ALDH1A1 (0.37) | ALDH1A1TDP1CA2 | |
| SCHEMBL9026605 | 0.68 | FOLH1 (0.34) | ALDH1A1TDP1CA2 | |
| SCHEMBL9026610 | 0.68 | FOLH1 (0.34) | ALDH1A1TDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |