Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31264411 | 0.81 | CTBP2 (0.71) | CTBP2CA1CA2HIF1ACA9 | |
| SCHEMBL9159740 | 0.78 | GAA (0.61) | PPIDL3MBTL1 | |
| SCHEMBL6156980 | 0.77 | CTBP2 (0.61) | CTBP2CA1CA2L3MBTL1 | |
| SCHEMBL6156969 | 0.77 | CTBP2 (0.61) | CTBP2CA1CA2L3MBTL1 | |
| SCHEMBL6156975 | 0.77 | CTBP2 (0.61) | CTBP2CA1CA2L3MBTL1 | |
| SCHEMBL9166257 | 0.75 | MGAM (0.40) | — | |
| Benzamide SCHEMBL28224034 | 0.74 | MAPT (0.53) | PPIDL3MBTL1 | |
| SCHEMBL5635989 | 0.74 | ALDH1A1 (0.59) | PPIDHIF1AL3MBTL1 | |
| SCHEMBL5635986 | 0.74 | ALDH1A1 (0.59) | PPIDHIF1AL3MBTL1 | |
| SCHEMBL319873 | 0.74 | PPID (0.54) | PPIDL3MBTL1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459142-A | Autoimmune disease, atherosclerosis, antiischemic agents and nephritis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| EP-0511879-B1 | Pyrazine derivatives | OTSUKA PHARMA CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| EP-0511879-A1 | Pyrazine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |