Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | CDK9 | P50750 | 1/20 | 0.64 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ACP1 | P24666 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359452 | 0.80 | TDP1 (0.53) | SMN1; SMN2TP53EPHX1KDM4EGAA | |
| SCHEMBL9274303 | 0.80 | MDM2 (0.67) | SMN1; SMN2EPHX1KDM4EGAARAB9A | |
| Diphenylurea SCHEMBL133103 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL3264574 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL8916095 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL3650947 | 0.78 | GAA (0.53) | SMN1; SMN2TP53KDM4EGAAMAOA | |
| SCHEMBL19834764 | 0.78 | RAB9A (0.60) | TSHRKDM4ERAB9ATAAR1NPC1 | |
| SCHEMBL11345729 | 0.78 | HSD17B10 (0.59) | SMN1; SMN2EPHX2GAACASP3SENP7 | |
| SCHEMBL9550361 | 0.77 | L3MBTL1 (0.61) | SMN1; SMN2KDM4EMAPTALDH1A1 | |
| Diphenylurea SCHEMBL3037927 | 0.77 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723522-B2 | Pyridine derivative production method | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2010-05-25 | — | — | US | disclosed |
| US-7723522-B2 | Pyridine derivative production method | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2010-05-25 | — | — | US | disclosed |
| US-5430147-A | Water-soluble anthraquinone compounds, preparation thereof, and use thereof as dyes | HOECHST AG (DE) | 1995-07-04 | — | — | US | disclosed |
| US-4529820-A | Cyanourea compounds | W. R. GRACE & CO. (US) | 1985-07-16 | — | — | US | disclosed |
| US-4465825-A | Thermosetting composition from cyanourea compound | W. R. GRACE & CO. (US) | 1984-08-14 | — | — | US | disclosed |
| US-4379728-A | ADHESIVE, SEALANT OR COATING | W. R. GRACE & CO. (US) | 1983-04-12 | — | — | US | disclosed |
| EP-0064479-A1 | Layered panel made from cellulosic material, and method of manufacturing the same | BATTELLE MEMORIAL INSTITUTE (CH) | 1982-11-10 | — | — | EP | disclosed |
| US-4304935-A | Production of 1-phenyl-3-cyanoureas | REXOLIN CHEMICALS AB (SE) | 1981-12-08 | — | — | US | disclosed |
| US-4304935-A | Production of 1-phenyl-3-cyanoureas | REXOLIN CHEMICALS AB (SE) | 1981-12-08 | — | — | US | disclosed |
| US-4304935-A | Production of 1-phenyl-3-cyanoureas | REXOLIN CHEMICALS AB (SE) | 1981-12-08 | — | — | US | disclosed |
| US-4098788-A | Process for preparing quinazolines | BRISTOL-MYERS COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4098788-A | Process for preparing quinazolines | BRISTOL-MYERS COMPANY (US) | 1978-07-04 | — | — | US | disclosed |