Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.45 |
| ▸ | P2RY10 | O00398 | 8/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951445 | 1.00 | PLA2G2C (0.45) | PLA2G2CP2RY10GPR34PLA2G2DGPR174 | |
| SCHEMBL9951880 | 1.00 | PLA2G2C (0.45) | PLA2G2CP2RY10GPR34PLA2G2DGPR174 | |
| SCHEMBL8628861 | 0.94 | P2RY10 (0.43) | P2RY10GPR34 | |
| SCHEMBL8627715 | 0.91 | S1PR1 (0.46) | P2RY10GPR34 | |
| SCHEMBL9166758 | 0.86 | PLA2G2C (0.43) | PLA2G2CP2RY10GPR34 | |
| SCHEMBL6372215 | 0.86 | PLA2G2C (0.46) | PLA2G2CP2RY10GPR34PLA2G2DGPR174 | |
| SCHEMBL15022342 | 0.86 | PLA2G2C (0.46) | PLA2G2CP2RY10GPR34PLA2G2DGPR174 | |
| SCHEMBL16964730 | 0.84 | P2RY10 (0.43) | PLA2G2CP2RY10GPR34 | |
| SCHEMBL17595343 | 0.83 | S1PR1 (0.49) | P2RY10GPR34 | |
| SCHEMBL9951988 | 0.83 | S1PR1 (0.49) | P2RY10GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845981-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | GENZYME CORPORATION (US) | 1998-06-10 | — | — | EP | claimed |
| WO-1997046223-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | GENZYME CORPORATION (US) | 1997-12-11 | — | — | WO | claimed |
| WO-2008089485-A2 | CARBOXYETHYLPYRROLE COMPOUNDS AND METHODS OF THEIR PRODUCTION | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008089487-A2 | CARBOXYETHYLPYRROLE COMPOUNDS AND METHODS OF THEIR PRODUCTION | THE CLEVELAND CLINIC FOUNDATION (US) | 2008-07-24 | — | — | WO | disclosed |
| EP-0845981-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | GENZYME CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997046223-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES | GENZYME CORPORATION (US) | 1997-12-11 | — | — | WO | disclosed |