SCHEMBL916722

SCHEMBL916722

O=P(O)(O)Cc1c(O)ccc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.61
CYP1A2 P05177 2/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
KDM4E B2RXH2 7/20 0.58
ALDH1A1 P00352 5/20 0.58
GAA P10253 5/20 0.58
MAPT P10636 5/20 0.58
TAAR1 Q96RJ0 1/20 0.58
GLA P06280 1/20 0.57
HPGD P15428 1/20 0.57
ACP3 P15309 1/20 0.56
TDP1 Q9NUW8 2/20 0.53
KMT2A Q03164 4/20 0.53
MEN1 O00255 1/20 0.53
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
PTPN22 Q9Y2R2 1/20 0.47
CYP2D6 P10635 1/20 0.46
HIF1A Q16665 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17029074 0.82 ACP3 (0.66) HSD17B10CYP1A2CYP2C9CYP2C19KDM4E
SCHEMBL28973814 0.81 ALDH1A1 (0.57) HSD17B10CYP1A2CYP2C9CYP2C19KDM4E
SCHEMBL915298 0.81 HSD17B10 (0.51) HSD17B10CYP1A2CYP2C9CYP2C19KDM4E
SCHEMBL8824574 0.81 ACP3 (0.54) HSD17B10CYP1A2CYP2C9CYP2C19KDM4E
SCHEMBL914870 0.79 ACP3 (0.56) HSD17B10CYP1A2CYP2C19KDM4EALDH1A1
SCHEMBL916426 0.78 WDR5 (0.54) HSD17B10KDM4EALDH1A1GAAGLA
SCHEMBL226196 0.77 HSD17B10 (0.76) HSD17B10CYP1A2CYP2C9CYP2C19KDM4E
SCHEMBL36762 0.77 HSD17B10 (1.00) HSD17B10CYP1A2CYP2C9CYP2C19KDM4E
SCHEMBL29357214 0.77 HSD17B10 (1.00) HSD17B10CYP1A2CYP2C9CYP2C19KDM4E
SCHEMBL3421056 0.76 SMN1; SMN2 (0.56) ALDH1A1ACP3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868126-B2 Process for producing polyester, polyester produced using said process, and polyester molded product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed
EP-1842868-B1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT TOYO BOSEKI (JP) 2010-11-10 EP disclosed
US-20090082529-A1 Polyester, Process for Producing Polyester, and Polyester Molded Article TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-03-26 US disclosed
US-20080249280-A1 Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
EP-1932867-A1 POLYESTER, PROCESS FOR PRODUCTION OF POLYESTER, AND POLYESTER MOLDED ARTICLE Toyo Boseki Kabushiki Kasisha (JP) 2008-06-18 EP disclosed
EP-1842868-A1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT Toyo Boseki Kabushiki Kasisha (JP) 2007-10-10 EP disclosed