Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 3/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cystine SCHEMBL6937787 | 0.79 | GPR35 (0.60) | GRM8GRM4KIF11GPR35KMO | |
| Cystine SCHEMBL6937795 | 0.79 | GPR35 (0.60) | GRM8GRM4KIF11GPR35KMO | |
| SCHEMBL6937789 | 0.74 | GRM8 (0.41) | GRM8GRM4GPR35KMO | |
| SCHEMBL12985822 | 0.72 | TSHR (0.40) | TSHRGPR35 | |
| SCHEMBL9064821 | 0.72 | GRM8 (0.49) | GRM8GRM4KIF11TSHRGPR35 | |
| SCHEMBL8138283 | 0.69 | ALDH1A1 (0.43) | KIF11TSHR | |
| SCHEMBL598438 | 0.68 | GRM8 (0.48) | GRM8GRM4GPR35 | |
| SCHEMBL8904293 | 0.66 | KDM4E (0.52) | GRM8GRM4KIF11TSHR | |
| SCHEMBL2003176 | 0.66 | KDM4E (0.52) | GRM8GRM4KIF11TSHR | |
| SCHEMBL8610040 | 0.66 | KDM4E (0.52) | GRM8GRM4KIF11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645138-A2 | Pharmaceutical composition for maintaining and/or reestablishing a rate of blood platelet aggregation clone to the normal value | Dehorne, Marthe (FR) | 1995-03-29 | — | — | EP | claimed |
| EP-0645138-A2 | Pharmaceutical composition for maintaining and/or reestablishing a rate of blood platelet aggregation clone to the normal value | Dehorne, Marthe (FR) | 1995-03-29 | — | — | EP | disclosed |
| US-4041150-A | OXIDATION | WILSON FOODS CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |