SCHEMBL9167809

SCHEMBL9167809

Oc1ccc(OC2(F)C(F)(F)C(F)(F)C2(F)Oc2ccc(O)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ESR1 P03372 2/20 0.46
LTA4H P09960 3/20 0.39
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
LMNA P02545 2/20 0.38
HIF1A Q16665 2/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
CA12 O43570 1/20 0.38
GMNN O75496 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38
CYP3A4 P08684 1/20 0.38
TYR P14679 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9175177 0.90 ESR2 (0.55) ESR2MEN1KMT2ALTA4HLMNA
SCHEMBL22680966 0.87 LMNA (0.54) ESR2MEN1KMT2AESR1LMNA
SCHEMBL12833562 0.86 MEN1 (0.38) ESR2MEN1KMT2AESR1LTA4H
SCHEMBL22681006 0.85 PKM (0.56) LMNAMAPTCA12ALDH1A1CA1
SCHEMBL9751696 0.79 ESR2 (0.44) ESR2MEN1KMT2AESR1LTA4H
SCHEMBL9169598 0.76 CA1 (0.52) MEN1KMT2ALTA4HMAPTKDM4E
SCHEMBL18337792 0.74 CA1 (0.50) KMT2ALMNACA12ALDH1A1CA1
SCHEMBL9171497 0.73 ALDH1A1 (0.37) KMT2AMAPTALDH1A1CA1CA2
SCHEMBL9806660 0.71 ESR2 (0.37) ESR2MEN1KMT2AESR1LTA4H
SCHEMBL9314140 0.71 CA12 (0.36) CA12CA1CA2CA4CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023009204-A1 COMPOSITIONS, METHODS FOR FORMING AN ARTICLE, AND PRODUCTS THEREOF QUADRATIC 3D, INC. (US) 2023-02-02 WO disclosed
EP-0428709-B1 REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS DOW CHEMICAL CO (US) 1995-05-24 EP disclosed
US-5210265-A Multistage reaction to form monomers for polymers such as polyesters by dimerization of trifluorovinyl compounds by dehalogenation and cyclization THE DOW CHEMICAL COMPANY (US) 1993-05-11 US disclosed
US-5198513-A Compounds for engineering thermoplastics or dimers THE DOW CHEMICAL COMPANY (US) 1993-03-30 US disclosed
US-5037919-A Endcapper for polyesters, polycarbonates, polyamides and polyethers THE DOW CHEMICAL COMPANY (US) 1991-08-06 US disclosed
EP-0429618-A1 REACTIVE COMPOUNDS CONTAINING PERFLUOROCYCLOBUTANE RINGS THE DOW CHEMICAL COMPANY (US) 1991-06-05 EP disclosed
US-5021602-A Monomers for condensation polymers THE DOW CHEMICAL COMPANY (US) 1991-06-04 US disclosed
EP-0428709-A1 REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS. DOW CHEMICAL CO (US) 1991-05-29 EP disclosed
WO-1990015044-A2 REACTIVE COMPOUNDS CONTAINING PERFLUOROCYCLOBUTANE RINGS THE DOW CHEMICAL COMPANY (US) 1990-12-13 WO disclosed
WO-1990015042-A2 REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS THE DOW CHEMICAL COMPANY (US) 1990-12-13 WO disclosed