Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22420948 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL17189971 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL7742363 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRGRIN2BCHRM2 | |
| SCHEMBL29896219 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL1AHRGRIN2BCHRM2 | |
| SCHEMBL2466203 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL16234253 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM2KDM4E | |
| SCHEMBL1872051 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL1AHRGRIN2BCHRM2 | |
| SCHEMBL221865 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRGRIN2BHRH1 | |
| SCHEMBL5854793 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRGRIN2BCHRM2 | |
| SCHEMBL16861945 | 0.70 | HRH1 (0.55) | SMN1; SMN2HRH1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494770-B1 | Method for preparing N-fluoropyridinium salts | ONODA CEMENT CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5336772-A | Reacting pyridine compound, fluorine and Bronsted acid in specified ratios | ONODA CEMENT CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0494770-A1 | Method for preparing N-fluoropyridinium salts | ONODA CEMENT COMPANY, LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |