Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16234253 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCYP1A2KDM4E | |
| SCHEMBL21191856 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1CYP1A2KDM4ELMNA | |
| SCHEMBL18427298 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1CYP1A2KDM4ELMNA | |
| SCHEMBL22420948 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1AHRKDM4EBLM | |
| SCHEMBL9168328 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1AHRCYP1A2KDM4E | |
| SCHEMBL7742363 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRCYP1A2KDM4E | |
| SCHEMBL9969506 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1AHRBLMCYP2D6 | |
| SCHEMBL8341980 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA | |
| SCHEMBL8146538 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1CYP1A2KDM4ELMNA | |
| SCHEMBL21742030 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1AHRCYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150299184-A1 | Amine Derivatives as Potassium Channel Blockers | BIONOMICS LIMITED (AU) | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299184-A1 | Amine Derivatives as Potassium Channel Blockers | KCNA3, KCNH3, KCNK3 | SMN1; SMN2 2666/4885L3MBTL1 3942/4885AHR 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.