Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31199233 | 0.77 | ACHE (0.44) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL2229729 | 0.77 | ACHE (0.44) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL31199230 | 0.76 | NPC1 (0.39) | LMNASMN1; SMN2ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL31199227 | 0.73 | S100A4 (0.47) | LMNAALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL9164065 | 0.73 | S100A4 (0.47) | LMNAALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL787128 | 0.71 | MEN1 (0.48) | LMNASMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL9163394 | 0.69 | CA12 (0.49) | SMN1; SMN2ALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL11892894 | 0.69 | SMN1; SMN2 (0.80) | LMNASMN1; SMN2ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL11881427 | 0.69 | SMN1; SMN2 (0.88) | LMNASMN1; SMN2ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL19396241 | 0.69 | SMN1; SMN2 (0.88) | LMNASMN1; SMN2ALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430164-B1 | Process for preparation of 2-substituted-1,4-naphthoquinone | NIPPON CATALYTIC CHEM IND (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-5329026-A | Oxidation of substituted naphthoquinone, adding a diene compound to reaction product, separation | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0430164-A2 | Process for preparation of 2-substituted-1,4-naphthoquinone | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |