⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28170782 | 0.72 | LMNA (0.43) | — | |
| SCHEMBL915523 | 0.69 | FAAH (0.45) | — | |
| SCHEMBL28109806 | 0.68 | TSHR (0.57) | — | |
| SCHEMBL28146576 | 0.66 | LMNA (0.47) | — | |
| SCHEMBL916845 | 0.66 | — | — | |
| SCHEMBL960130 | 0.60 | TSHR (0.61) | — | |
| SCHEMBL7077558 | 0.60 | CYP2D6 (0.36) | — | |
| SCHEMBL5023753 | 0.60 | KDM4E (0.35) | — | |
| SCHEMBL28560889 | 0.59 | LMNA (0.36) | — | |
| SCHEMBL27817396 | 0.59 | MEN1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868116-B2 | Process for the production of high-molecular-weight organopolysiloxanes | WACKER CHEMIE AG (DE) | 2011-01-11 | — | — | US | disclosed |
| US-7582700-B2 | Method for the production of emulsions of highly-viscous organopolysiloxanes | WACKER CHEMIE AG (DE) | 2009-09-01 | — | — | US | disclosed |
| US-20090198034-A1 | PROCESS FOR THE PRODUCTION OF HIGH-MOLECULAR-WEIGHT ORGANOPOLYSILOXANES | WACKER CHEMIE AG (DE) | 2009-08-06 | — | — | US | disclosed |
| US-20080033062-A1 | Method for the Production of Emulsions of Highly-Viscous Organopolysiloxanes | WACKER CHEMIE AG (DE) | 2008-02-07 | — | — | US | disclosed |