Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91669 | 0.95 | KMT2A (0.35) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL91696 | 0.93 | CYP1A2 (0.33) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL91677 | 0.91 | CYP1A2 (0.32) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL91676 | 0.78 | LMNA (0.34) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL91661 | 0.74 | KMT2A (0.39) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL17355723 | 0.74 | KMT2A (0.41) | KMT2AMEN1ALDH1A1CYP3A4HPGD | |
| SCHEMBL25573712 | 0.74 | GABRA1 (0.36) | — | |
| SCHEMBL19891866 | 0.73 | FFAR4 (0.32) | — | |
| SCHEMBL24390818 | 0.72 | RAPGEF4 (0.33) | — | |
| SCHEMBL91785 | 0.71 | MAPT (0.35) | KMT2AMEN1ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7419706-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-02 | — | — | US | disclosed |