Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170928 | 0.96 | ACE (0.46) | ACEPPARGPPARAALDH1A1GRIA1 | |
| SCHEMBL9166218 | 0.91 | TLR2 (0.48) | ACEGRIA1 | |
| SCHEMBL9164248 | 0.91 | TLR2 (0.48) | ACEGRIA1 | |
| SCHEMBL9169293 | 0.90 | TLR2 (0.47) | ACEPPARGPPARAGRIA1 | |
| SCHEMBL9174024 | 0.88 | CHRNB2 (0.45) | ACEPPARGPPARAGRIA1 | |
| SCHEMBL9170095 | 0.84 | GLO1 (0.49) | ACEPPARGPPARA | |
| SCHEMBL9167736 | 0.82 | ACE (0.46) | ACEPPARGPPARA | |
| SCHEMBL9165661 | 0.81 | ACE (0.60) | ACEPPARGPPARA | |
| SCHEMBL9171784 | 0.81 | ACE (0.60) | ACEPPARGPPARA | |
| SCHEMBL9167734 | 0.80 | ACE (0.46) | ACEPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455833-B1 | AMINO ACID DERIVATIVE | SANTEN PHARMACEUTICAL CO LTD (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5214181-A | Immunodeficiency and autoimmune disease treatment | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |