Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.45 |
| ▸ | CHRNG | P07510 | 4/20 | 0.45 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.45 |
| ▸ | CHRND | Q07001 | 4/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164248 | 0.99 | TLR2 (0.48) | TLR2CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL9166218 | 0.99 | TLR2 (0.48) | TLR2CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL9174024 | 0.97 | CHRNB2 (0.45) | TLR2CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL9170928 | 0.94 | ACE (0.46) | GRIA1ACEPPARGPPARA | |
| SCHEMBL9169284 | 0.90 | ACE (0.43) | GRIA1ACEPPARGPPARA | |
| SCHEMBL9172971 | 0.86 | ACE (0.49) | MMP1MMP3MMP9ACEPPARG | |
| SCHEMBL9167736 | 0.84 | ACE (0.46) | ACEPPARGPPARA | |
| SCHEMBL9170095 | 0.84 | GLO1 (0.49) | ACEPPARGPPARA | |
| SCHEMBL9169296 | 0.82 | PPARG (0.41) | MMP1MMP3MMP9ACEPPARG | |
| SCHEMBL9166230 | 0.82 | MMP2 (0.41) | MMP1MMP3MMP9ACEPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455833-B1 | AMINO ACID DERIVATIVE | SANTEN PHARMACEUTICAL CO LTD (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5214181-A | Immunodeficiency and autoimmune disease treatment | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |