Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145506 | 0.98 | CALM1 (0.64) | CALM1LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL10569250 | 0.96 | CALM1 (0.62) | CALM1LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL27914349 | 0.96 | CALM1 (0.68) | CALM1LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL10571667 | 0.94 | CALM1 (0.60) | CALM1LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL13579997 | 0.92 | MAOB (0.63) | CALM1LMNAGAAMEN1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL9061621 | 0.92 | CASP3 (0.59) | CALM1LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL581719 | 0.91 | CASP3 (0.63) | CALM1LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL10568997 | 0.91 | CASP3 (0.63) | CALM1LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL10534584 | 0.89 | CASP3 (0.61) | CALM1LMNAGAAMEN1ALDH1A1 | |
| SCHEMBL10533113 | 0.89 | CASP3 (0.61) | CALM1LMNAGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101222916-A | Phenol derivatives and their use to modulate PKB activity | IMP INNOVATIONS LTD (GB) | 2008-07-16 | — | — | CN | disclosed |
| EP-0443606-B1 | 4-(4-alkoxyphenyl)-2-butylamine derivatives and process therefor | SHIONOGI & CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5073648-A | Intermediates for dopamine derivatives | SHIONOGI & CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0443606-A2 | 4-(4-alkoxyphenyl)-2-butylamine derivatives and process therefor | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |