Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317843 | 0.91 | SMN1; SMN2 (0.40) | SMN1; SMN2TP53RAB9ANPC1KMT2A | |
| SCHEMBL9169891 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53RAB9ANPC1PTGDR2 | |
| SCHEMBL9169904 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53RAB9ANPC1PTGDR2 | |
| SCHEMBL9168771 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53RAB9ANPC1PTGDR2 | |
| SCHEMBL9168779 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53RAB9ANPC1PTGDR2 | |
| SCHEMBL9523771 | 0.79 | ALDH1A1 (0.51) | SMN1; SMN2TP53KMT2AMEN1HPGD | |
| SCHEMBL9170254 | 0.78 | NPSR1 (0.41) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL9168897 | 0.77 | PTGS2 (0.43) | SMN1; SMN2TP53PTGDR2HPGDPOLB | |
| SCHEMBL9164209 | 0.75 | HIF1A (0.43) | SMN1; SMN2TP53RAB9ANPC1KMT2A | |
| SCHEMBL9164204 | 0.75 | HIF1A (0.43) | SMN1; SMN2TP53RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606228-B1 | PROPENOIC ACID DERIVATIVES | AGREVO UK LTD (GB) | 1995-04-12 | — | — | EP | disclosed |
| WO-1992021653-A1 | PROPENOIC ACID DERIVATIVES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-12-10 | — | — | WO | disclosed |
| EP-0517301-A1 | Propenoic acid derivatives | AgrEvo UK Limited (GB) | 1992-12-09 | — | — | EP | disclosed |