Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170004 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2TP53L3MBTL1KMT2AKDM4E | |
| SCHEMBL9523771 | 0.79 | ALDH1A1 (0.51) | SMN1; SMN2TP53L3MBTL1KMT2AKDM4E | |
| SCHEMBL9170254 | 0.78 | NPSR1 (0.41) | SMN1; SMN2L3MBTL1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8822600 | 0.77 | L3MBTL1 (0.58) | SMN1; SMN2L3MBTL1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9169891 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53L3MBTL1KMT2AKDM4E | |
| SCHEMBL9169904 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2TP53L3MBTL1KMT2AKDM4E | |
| SCHEMBL27317023 | 0.74 | NPC1 (0.44) | SMN1; SMN2L3MBTL1KMT2AALDH1A1PKM | |
| SCHEMBL9168779 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53L3MBTL1KMT2AKDM4E | |
| SCHEMBL9168771 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53L3MBTL1KMT2AKDM4E | |
| SCHEMBL8636885 | 0.72 | L3MBTL1 (0.41) | SMN1; SMN2L3MBTL1KMT2AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606228-A1 | PROPENOIC ACID DERIVATIVES. | AGREVO UK LTD (GB) | 1994-07-20 | — | — | EP | disclosed |