Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.32 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.32 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170481 | 1.00 | TSHR (0.37) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL11667699 | 0.81 | TSHR (0.39) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL6838883 | 0.80 | TSHR (0.39) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL29710697 | 0.79 | — | — | |
| SCHEMBL149514 | 0.79 | — | — | |
| SCHEMBL9175808 | 0.78 | CYP3A4 (0.33) | TSHRCYP3A4MAPTCACNA1BAPBA1 | |
| SCHEMBL9175802 | 0.78 | CYP3A4 (0.33) | TSHRCYP3A4MAPTCACNA1BAPBA1 | |
| Acetic Acid SCHEMBL28514941 | 0.75 | TSHR (0.41) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL1077904 | 0.75 | GLO1 (0.48) | TSHRMAPTALDH1A1HSD17B10GLO1 | |
| SCHEMBL8282623 | 0.75 | GLO1 (0.48) | TSHRMAPTALDH1A1HSD17B10GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9862978-B2 | Method for preparing (2RS)-amino-(3S)-hydroxy-butyric acid and its derivatives | AMINOLOGICS CO. LTD. (KR) | 2018-01-09 | — | — | US | claimed |
| US-20160017389-A1 | METHOD FOR PREPARING (2RS)-AMINO-(3S)-HYDROXY-BUTYRIC ACID AND ITS DERIVATIVES | AMINOLOGICS CO., LTD. (KR) | 2016-01-21 | — | — | US | claimed |
| US-9862978-B2 | Method for preparing (2RS)-amino-(3S)-hydroxy-butyric acid and its derivatives | AMINOLOGICS CO. LTD. (KR) | 2018-01-09 | — | — | US | disclosed |
| US-20160017389-A1 | METHOD FOR PREPARING (2RS)-AMINO-(3S)-HYDROXY-BUTYRIC ACID AND ITS DERIVATIVES | AMINOLOGICS CO., LTD. (KR) | 2016-01-21 | — | — | US | disclosed |
| EP-0669927-A1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS | ANTIVIRALS INC. (US) | 1995-09-06 | — | — | EP | disclosed |
| EP-0382220-B1 | Method for preparing aminothiazolylacetic acid derivatives | MEIJI SEIKA KAISHA (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5405938-A | Hydrogen bonding an N-heterocyclic-substituted ribose-based polymer to a double-stranded DNA to block genetic activity, to diagnose for pathogens and to aid in genetic engineering | ANTI-GENE DEVELOPMENT GROUP (US) | 1995-04-11 | — | — | US | disclosed |
| WO-1994012517-A1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS | ANTIVIRALS INC. (US) | 1994-06-09 | — | — | WO | disclosed |
| US-4161591-A | SUBSTITUTED 2-(CARBAMOYL)OXYIMINO-3-IMINO-BUTYRAMIDES AND -BUTYRATES, APHIDICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-07-17 | — | — | US | disclosed |
| US-4161591-A | SUBSTITUTED 2-(CARBAMOYL)OXYIMINO-3-IMINO-BUTYRAMIDES AND -BUTYRATES, APHIDICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-07-17 | — | — | US | disclosed |
| US-4151296-A | APHIDICIDES, SYSTEMIC AND FOLIAR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4151296-A | APHIDICIDES, SYSTEMIC AND FOLIAR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4059623-A | APHIDICIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-11-22 | — | — | US | disclosed |
| US-4059623-A | APHIDICIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160017389-A1 | METHOD FOR PREPARING (2RS)-AMINO-(3S)-HYDROXY-BUTYRIC ACID AND ITS DERIVATIVES | ALAD, CYP51A1, ALDH7A1 | TSHR 2466/4885CYP3A4 56/4885TDP1 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.