Sugi Predict

Sugi Predict / Compounds / SCHEMBL1077904

SCHEMBL1077904

SCHEMBL1077904

CCOC(=O)/C(=N\O)C(C)=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GLO1 Q04760 1/20 0.48
▸ ALDH1A1 P00352 4/20 0.44
▸ LMNA P02545 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ MAPT P10636 3/20 0.44
▸ NPSR1 Q6W5P4 2/20 0.39
▸ APOBEC3A P31941 1/20 0.39
▸ APOBEC3G Q9HC16 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ TSHR P16473 2/20 0.38
▸ ABCB1 P08183 1/20 0.38
▸ ALOX15 P16050 1/20 0.37
▸ MGAM O43451 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ SI P14410 1/20 0.37
▸ MGAM2 Q2M2H8 1/20 0.37
▸ SOAT1 P35610 1/20 0.37
▸ EGLN1 Q9GZT9 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.35
▸ GLA P06280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8282623 1.00 GLO1 (0.48) GLO1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL1077905 1.00 GLO1 (0.48) GLO1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL2914885 0.88 ALDH1A1 (0.46) GLO1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL11509629 0.84 MAPT (0.47) GLO1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL11509628 0.84 MAPT (0.47) GLO1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL27280953 0.83 TSHR (0.37) GLO1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL14159229 0.82 EGLN1 (0.41) GLO1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL9061777 0.82 GLO1 (0.48) GLO1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL7766368 0.80 SOAT1 (0.41) GLO1ALDH1A1LMNAHSD17B10MAPT
SCHEMBL7766372 0.80 SOAT1 (0.41) GLO1ALDH1A1LMNAHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117326974-B Preparation method of ethyl 2-hydroxyiminoacetoacetate 山东国邦药业有限公司 2024-02-13 — — CN claimed
CN-117326974-A Preparation method of ethyl 2-hydroxyiminoacetoacetate 山东国邦药业有限公司 2024-01-02 — — CN claimed
US-11713300-B2 Platelet aggregation inhibitor, preparation and uses thereof SHENYANG HINEWY PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2023-08-01 — — US claimed
CN-116283655-A Continuous production process and system of ethyl 2-hydroxy imine acetoacetate 青岛科技大学 2023-06-23 — — CN claimed
US-12528784-B2 Alkynyl-(heteroaryl)-carboxamide HCN1 inhibitors HOFFMANN-LA ROCHE INC. (US) 2026-01-20 — — US disclosed
EP-4642785-A1 IL-17A MODULATORS Usynova Pharmaceuticals Ltd. (CN) 2025-11-05 — — EP disclosed
US-20250320216-A1 PHOSPHODIESTERASE INHIBITORS AND USES THEREOF TOPADUR PHARMA AG (CH) 2025-10-16 — — US disclosed
US-12351585-B2 2-phenyl-3,4-dihydropyrrolo[2,1-f] [1,2,4]triazinone derivatives as phosphodiesterase inhibitors and uses thereof TOPADUR PHARMA AG (CH) 2025-07-08 — — US disclosed
CN-114746408-B Alkynyl- (heteroaryl) -carboxamide HCN1 inhibitors 豪夫迈·罗氏有限公司 2025-02-14 — — CN disclosed
US-20240343730-A1 2-PHENYL-3,4-DIHYDROPYRROLO[2,1 -F] [1,2,4]TRIAZINONE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS AND USES THEREOF TOPADUR PHARMA AG (CH) 2024-10-17 — — US disclosed
WO-2024139171-A1 IL-17A MODULATORS USYNOVA PHARMACEUTICALS, LTD. (CN) 2024-07-04 — — WO disclosed
WO-2024138286-A1 IL-17A MODULATORS USYNOVA PHARMACEUTICALS, LTD. (CN) 2024-07-04 — — WO disclosed
US-4166115-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1979-08-28 — — US disclosed
EP-0002605-A1 Cephalosporin compounds and formulations containing them for use in the treatment of bacterial infections and the preparation of the cephalosporin compounds ELI LILLY AND COMPANY (US) 1979-06-27 — — EP disclosed
US-4152432-A ANTIBIOTICS ROUSSEL UCLAF (FR) 1979-05-01 — — US disclosed
US-4113946-A Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-09-12 — — US disclosed
US-4066831-A ANTIBIOTICS BRISTOL-MYERS COMPANY (US) 1978-01-03 — — US disclosed
US-4065623-A O-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1977-12-27 — — US disclosed
US-4012383-A BACTERICIDES BRISTOL-MYERS COMPANY (US) 1977-03-15 — — US disclosed
US-4010178-A Carbonic acid esters, and the preparation thereof and their use FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528784-B2 Alkynyl-(heteroaryl)-carboxamide HCN1 inhibitors HCN1, HCN2, HCN3 GLO1 2859/4885ALDH1A1 529/4885LMNA 353/4885
US-20240343730-A1 2-PHENYL-3,4-DIHYDROPYRROLO[2,1 -F] [1,2,4]TRIAZINONE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS AND USES THEREOF PDE7A, PDE3A, GNAO1 GLO1 3085/4885ALDH1A1 623/4885LMNA 2493/4885
US-20250320216-A1 PHOSPHODIESTERASE INHIBITORS AND USES THEREOF PDE7A, PDE3A, PDE3B GLO1 2789/4885ALDH1A1 702/4885LMNA 2421/4885
US-11713300-B2 Platelet aggregation inhibitor, preparation and uses thereof TFPI, F12, TFPI2 GLO1 2074/4885ALDH1A1 1546/4885LMNA 2219/4885
US-12351585-B2 2-phenyl-3,4-dihydropyrrolo[2,1-f] [1,2,4]triazinone derivatives as phosphodiesterase inhibitors and uses thereof PDE7A, PDE3A, GNAO1 GLO1 3085/4885ALDH1A1 623/4885LMNA 2493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.